He is a psychiatrist, researcher, professor, and consultant. He currently serves as Head of the Department of Psychiatry at the University of São Paulo School of Medicine (FMUSP) and as an Adjunct Associate Professor at the Child Study Center of Yale Medical School.

He previously served as an Adjunct Associate Professor in the Department of Psychiatry at Duke University, as a research consultant at Massachusetts General Hospital, Harvard University, and founded the Obsessive-Compulsive Spectrum Disorders Program (PROTOC). He leads research projects focused on Obsessive-Compulsive Disorder (OCD), coordinates the Brazilian Obsessive-Compulsive Spectrum Disorders Research Consortium (C-TOC), and participates in international consortia such as ENIGMA-OCD and OBIC.

He is the principal investigator of a project funded by the U.S. National Institute of Mental Health (NIMH) focused on identifying the genetic signature of OCD in a diverse sample of 5,000 patients from Latin America. Since 2009, he has led the Child and Adolescent Psychiatry field, which culminated in the creation of the National Institute of Developmental Psychiatry (INPD) in 2009.

He is Editor Emeritus of the Brazilian Journal of Psychiatry and a member of the American College of Neuropsychopharmacology, the Society of Biological Psychiatry, and the Brazilian Psychiatric Association.

At CISM, he serves as Coordinator.